Bayer AG
Postdoc DMPK (in vitro ADME & IC) - Proteomics (all genders)
Wuppertal-Aprath, DEPosted 6 days ago
Full TimeSeniorDE
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Job Description
Bayer is a global enterprise with core competencies in the Life Science fields of health care and agriculture. Its products and services are designed to benefit people and improve their quality of lif
Key Highlights
- You will use proteomics methods to support research projects addressing on- and off-target profiles, target occupancy, targeted protein degradation, and related questions
- You will establish and optimize proteomics techniques (both new methods and improvements to existing workflows) to elucidate disease mechanisms and to characterize PK/PD and PK/TK relationships for novel modalities, e.g., covalent binders
- You will implement multi‑omics approaches within preclinical development to support the design, evaluation and interpretation of preclinical safety and toxicology studies
- You hold a PhD in life sciences (biology, protein biochemistry, analytical chemistry, or a related field)
- You have a strong background in untargeted (with a focus on DIA) and targeted proteomics, covering sample preparation, data acquisition and data analysis (experience with Proteome Discoverer, Spectronaut, Skyline)
Qualifications
Required Qualifications
- You hold a PhD in life sciences (biology, protein biochemistry, analytical chemistry, or a related field)
- You have a strong background in untargeted (with a focus on DIA) and targeted proteomics, covering sample preparation, data acquisition and data analysis (experience with Proteome Discoverer, Spectronaut, Skyline)
- You have hands‑on experience with nano LC and high‑resolution mass spectrometry, preferably Orbitrap instruments
- You are experienced in handling, annotating and visualizing complex proteomics datasets, using bioinformatics tools such as R and Python (knowledge of annotation resources like KEGG, GO)
- Experience with automated sample preparation is an advantage
- Basic knowledge of drug metabolism and pharmacokinetics is an advantage
- You apply scientific rigor and are efficient, creative and highly organized
- You have a collaborative mindset and are a team player in interdisciplinary settings
- You communicate and present clearly and confidently
- You have excellent English skills, both spoken and written
Skills & Technologies
GoPython
About the Company
Bayer AG
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Job Details
Employment Type
Full Time
Experience Level
Senior
Location
Wuppertal-Aprath, DE
Posted
6 days ago
Country
DE