KU - SUND - PANUM KBH N

PhD position for 3 years in stem cell-based disease modelling of the hypothalamus

København N, DanmarkPosted 1 day ago
Full TimeSeniorDK

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Job Description

Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW) Faculty of Health and Medical Sciences University of Copenhagen Position: PhD position, full-time, 3 years Start: 15/12-2026 or upon agree

Key Highlights

  • Culturing and subtype-specific differentiation of human pluripotent stem cells into neurons ad glial cells
  • Quality control of neuronal subtypes in the dish through qRT-PCR and immunocytochemistry
  • Scaling up of stem cell cultures to high-throughput multiwell format for automated analysis
  • High-throughput screening of peptides and small molecules in the dish for identification of hypothalamic GPCRs with appetite-regulating roles
  • Proximity labelling in stem cell models using gene edited cell lines and proteomics

Qualifications

Required Qualifications

  • Experience in working with 3D/organoid cultures
  • Experience in high-throughput screening assays and high-content image analysis
  • Experience in working with intracellular cAMP assays
  • Experience in working with assessment of neuronal connectivity, synapse formation or neuronal function (i.e. electrophysiology or MEA)
  • Experience in qRT-PCR, ICC, confocal imaging and automated image analysis

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Job Details

Employment Type

Full Time

Experience Level

Senior

Location

København N, Danmark

Posted

1 day ago

Country

DK