Principal Scientist (all genders) Structural Biology

Required Qualifications

• PhD in Structural Biology or a related field with 10+ years of relevant experience (including biopharma, biotech) and strong track record to design, execute and drive complex structural biology projects.
• Deep expertise in high-resolution structure determination of proteins and protein complexes by Xray crystallography (sample generation, data collection & processing, structure refinement with industry-standard software).
• Experience working with antigen–antibody and protein degrader complexes, with a deep understanding of structure–function relationships.
• Ideally hands-on with single-particle cryo-EM and biophysical (e.g. HDX-MS, SAXS; Refeyn, FIDA, DSF)
• Experience with cloud-based/HPC data management and processing; LINUX scripting; AI/ML-based prediction of biomolecular structures.
• Effective collaborator and leader in multidisciplinary settings with excellent English communication; skilled in guiding/mentoring scientists, coordinating multi-site work, and managing CROs to balance project demands.
• Proven ability to convey complex data clearly to drive decisions; strong publication history or impactful drug discovery contributions (oncology/immunology/neuroscience favored); excellent problem-solving abilities and experience introducing relevant new technologies.